It is not known whether acarbose passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using acarbose. Digestive Tract: Gastrointestinal symptoms are the most common reactions to Acarbose Tablets. ULN, and greater than 3 times the ULN occurred in 14%, 6%, and 3%, respectively, of Acarbose Tablets-treated patients as compared to 7%, 2%, and 1%, respectively, of placebo-treated patients. Although these differences between treatments were statistically significant, these elevations were asymptomatic, reversible, more common in females, and, in general, were not associated with other evidence of liver dysfunction. In addition, these serum transaminase elevations appeared to be dose related. wibex.info flagyl
To evaluate the long-term efficacy of precose in improving glycemic control in subjects with NIDDM, a one-year, multicenter, randomized, double-blind, placebo-controlled study was conducted. The study involved 354 subjects with NIDDM. Clinical studies demonstrated a strong association between hyperglycemia and an increased risk of microvascular tissue damage. Trials involving Precose established that hemoglobin levels are a more significant predictor of the onset or progression of retinopathy in NIDDM diabetic patients than blood glucose concentration. Precose significantly reduced hemoglobin levels in NIDDM subjects maintained on dietary therapy alone. The magnitude of the treatment effect steadily increased during active treatment; diabetic retinopathy was reduced by approximately 30%.
Pediatric Use: Safety and effectiveness of Acarbose Tablets in pediatric patients have not been established. Some medical conditions may interact with acarbose. Acarbose Tablets themselves do not cause hypoglycemia even when administered to patients in the fasted state. Sulfonylurea drugs and insulin, however, can lower blood sugar levels enough to cause symptoms or sometimes life-threatening hypoglycemia. Because Acarbose Tablets given in combination with a sulfonylurea or insulin will cause a further lowering of blood sugar, it may increase the hypoglycemic potential of these agents. Hypoglycemia does not occur in patients receiving metformin alone under usual circumstances of use, and no increased incidence of hypoglycemia was observed in patients when Acarbose Tablets were added to metformin therapy. The risk of hypoglycemia, its symptoms and treatment, and conditions that predispose to its development should be well understood by patients and responsible family members.
Also watch for signs of high blood sugar hyperglycemia such as increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, and weight loss. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Your pharmacist can provide more information about acarbose.
Store at room temperature below 77 degrees F 25 degrees C away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets. After gastric surgery, it can be more difficult to regulate movement of food, which dumps too quickly into the small intestine. Eating certain foods makes dumping syndrome more likely. For example, refined sugars rapidly absorb water from the body, causing symptoms. Symptoms may also happen after eating dairy products and certain fats or fried foods. Acarbose Tablets are available as 25 mg, 50 mg and 100 mg for oral use. The inactive ingredients are starch, microcrystalline cellulose, magnesium stearate, and colloidal silicon dioxide. Acarbose Tablets should be adjusted at 4-8 week intervals based on one-hour postprandial glucose or glycosylated hemoglobin levels, and on tolerance. Because its mechanism of action is different, the effect of Acarbose Tablets to enhance glycemic control is additive to that of sulfonylureas, insulin or metformin when used in combination. In addition, Acarbose Tablets diminish the insulinotropic and weight-increasing effects of sulfonylureas. Tell your doctor if you have ever had any unusual or allergic reaction to acarbose or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Geriatric Use: Of the total number of subjects in clinical studies of Acarbose Tablets in the United States, 27% were 65 and over, while 4% were 75 and over. No overall differences in safety and effectiveness were observed between these subjects and younger subjects. Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Keep a recent prescription and your medical history with you. Be prepared for an emergency as you would normally. Make allowances for changing time zones and keep your meal times as close as possible to your usual meal times. Keep all medicines away from children and pets. About FAERS: The FDA Adverse Event Reporting System FAERS is used by FDA for activities such as looking for new safety concerns that might be related to a marketed product, evaluating a manufacturer's compliance to reporting regulations and responding to outside requests for information. Reporting of adverse events is a voluntary process, and not every report is sent to FDA and entered into FAERS.
The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Always consult your doctor or healthcare specialist for medical advice. What is acarbose Precose? Discuss the risks and benefits with your doctor. Use and dose must be determined by your doctor. Acarbose does not usually cause low blood sugar. Low blood sugar may be more likely to occur if you skip a meal, exercise heavily, or drink alcohol. It may also be more likely if you take acarbose along with certain medicines for diabetes eg, sulfonylureas, insulin. Tell your doctor right away if you experience symptoms of low blood sugar eg, fast heartbeat, headache, chills, sweating, tremors, increased hunger, vision changes, nervousness, weakness, dizziness, drowsiness, fainting. It is a good idea to carry a reliable source of glucose eg, tablets or gel to treat low blood sugar. This will raise your blood sugar level quickly. Because acarbose prevents the breakdown of table cane sugar, be sure to use glucose dextrose not sugar or fruits, to treat symptoms of low blood sugar. Contact your health care provider if you have any questions. The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables. Acarbose corresponding to 10 times the dose in man, based on body surface area showed no evidence of embryotoxicity and there was no evidence of teratogenicity at a dose 32 times the dose in man based on body surface area. There are, however, no adequate and well-controlled studies of Acarbose Tablets in pregnant women. Because animal reproduction studies are not always predictive of the human response, this drug should be used during pregnancy only if clearly needed. Because current information strongly suggests that abnormal blood glucose levels during pregnancy are associated with a higher incidence of congenital anomalies as well as increased neonatal morbidity and mortality, most experts recommend that insulin be used during pregnancy to maintain blood glucose levels as close to normal as possible. Do not keep outdated medicine or medicine no longer needed. This list is not complete. Other drugs may interact with acarbose, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. Overdose symptoms may include bloating, gas, or stomach discomfort. What is the most important information I should know about acarbose Precose? Doing so can irritate the and also change the way the medication works. Tell your doctor about all kind of medications you are taking, as these may interfere with the ability of Glycomet Generic Glucomin to control your blood sugar level. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. fenofibrate
Do not use this medication if you are allergic to acarbose, or if you are in a state of diabetic ketoacidosis call your doctor for treatment with insulin. You also should not use acarbose if you have inflammatory bowel disease, an ulcer or blockage in your intestines, or cirrhosis of the liver. Using acarbose with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. Acarbose Tablets should be taken three times daily at the start with the first bite of each main meal. Acarbose Tablets should be started at a low dose, with gradual dose escalation as described below, both to reduce gastrointestinal side effects and to permit identification of the minimum dose required for adequate glycemic control of the patient. If the prescribed diet is not observed, the intestinal side effects may be intensified. If strongly distressing symptoms develop in spite of adherence to the diabetic diet prescribed, the doctor must be consulted and the dose temporarily or permanently reduced. Follow carefully the special meal plan your doctor gave you. This is the most important part of controlling your condition, and is necessary if the medicine is to work properly. Also, exercise regularly and test for sugar in your blood or urine as directed. Carry hard candy or glucose tablets with you in case you have low blood sugar. Other sugar sources include orange juice and milk. Be sure your family and close friends know how to help you in an emergency. Take acarbose with the first bite of a main meal, unless your doctor tells you otherwise. If you miss a dose of acarbose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. If you miss a dose of acarbose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Precose slows the digestion of carbohydrate sugars and starches in the small intestine. You should take the prescribed dose with the FIRST BITE of each main meal. A small dose will be started and your health care provider will gradually increase it as needed. Your health care provider may want you to combine Precose with another type of diabetes pill. Since Precose works differently than the other diabetes pills, it will not interfere with their action. Combined with these pills, Precose may further improve your control. Tell your doctor or dentist that you take acarbose before you receive any medical or dental care, emergency care, or surgery. Before taking acarbose, tell your doctor if you have liver disease, or any type of stomach or intestinal disorder. Some MEDICINES MAY INTERACT with acarbose. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs including any herbal medicines or supplements or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. Take the missed dose as soon as you remember be sure to take it with a meal. If it has been longer than 15 minutes since you started your meal, you may still take acarbose but it may be less effective than taking it with the first bite of the meal. Do not take acarbose between meals, and do not take extra medicine to make up a missed dose. What happens if I overdose?
Use sugar replacements, such as Splenda, Equal, or Sweet'N Low, instead of sugar. Check your blood sugar carefully during times of stress, travel, illness, surgery or medical emergency, vigorous exercise, or if you drink alcohol or skip meals. These things can affect your glucose levels and your dose needs may also change. Do not change your medication dose or schedule without your doctor's advice. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Take this medication by with meals and snacks as directed by your doctor. Swallow the capsule whole. Sulfonylurea agents or insulin may cause hypoglycemia. Acarbose Tablets are contraindicated in patients with known hypersensitivity to the drug. Acarbose Tablets are contraindicated in patients with diabetic ketoacidosis or cirrhosis. Acarbose Tablets are also contraindicated in patients with inflammatory bowel disease, colonic ulceration, partial intestinal obstruction or in patients predisposed to intestinal obstruction. In addition, Acarbose Tablets are contraindicated in patients who have chronic intestinal diseases associated with marked disorders of digestion or absorption and in patients who have conditions that may deteriorate as a result of increased gas formation in the intestine. Take at the start with first bite of each main meal; patients should be adhering to a diabetic diet to minimize GI side effects. Acarbose Tablets are indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. Glycomet is used to treat type 2 noninsulin-dependent diabetes. Glycomet Glucomin decreases the amount of glucose you absorb from your food and the amount of glucose made by your liver. Glycomet Glucomin increases your body's response to insulin, a natural substance that controls the amount of glucose in the blood. Check your blood sugar carefully during a time of stress or illness, if you travel, exercise more than usual, drink alcohol, or skip meals. These things can affect your glucose levels and your dose needs may also change. What happens if I overdose Precose? If you take acarbose with insulin or other diabetes medications, your blood sugar could get too low. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Eat five or six small meals or snacks a day. mirtazapine tablets order online shop
Professor Rury Holman, co-director of the UKPDS, said that patients experienced a very similar reduction in HbA1c over the three-year study period regardless of which existing therapy Precose was added to -- insulin, sulphonylurea, metformin or diet alone. Cut food into very small pieces. Chew well before swallowing. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking acarbose, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. It is important to manage dumping syndrome so you stay well-nourished and don't lose too much weight. Talk to your provider about any symptoms you have and what else you can do. In some cases, or surgery may be needed to help correct the symptoms of dumping syndrome. Patients Receiving Sulfonylureas or Insulin: Sulfonylurea agents or insulin may cause hypoglycemia. Acarbose Tablets given in combination with a sulfonylurea or insulin will cause a further lowering of blood glucose and may increase the potential for hypoglycemia. If hypoglycemia occurs, appropriate adjustments in the dosage of these agents should be made.
At first the dose is 25 milligrams mg three times a day, at the start of each main meal. Your dose may then be adjusted by your doctor. Other symptoms of low blood sugar such as dizziness, hunger, and sweating are unaffected by these drugs. You may be more likely to have hyperglycemia high blood sugar if you are taking acarbose with other drugs that raise blood sugar. Teratogenic Effects: Pregnancy Category B. The safety of Acarbose Tablets in pregnant women has not been established. Your doctor may want you to stop taking acarbose for a short time if you become ill, have a fever or infection, or if you have surgery or a medical emergency. AIMS: Thioctic acid TA glibenclamide and acarbose are widely used to either alone or concomitantly treat patients suffering from noninsulin-dependent diabetes NIDDM. This study systematically investigated drug-drug interactions between TA and glibenclamide and TA and acarbose. METHODS: Fourteen male and 10 female healthy volunteers participated a randomized, open three period cross over trial treatments A-C followed by a fourth period treatment D. A baseline profile for plasma insulin and glucose concentrations, variables which served as pharmacodynamic measures, was assessed before entering the trial. Water pulled out of the bloodstream moves into the small intestine. In a one-year safety study, during which patients kept diaries of gastrointestinal symptoms, abdominal pain and diarrhea tended to return to pretreatment levels over time, and the frequency and intensity of flatulence tended to abate with time. The increased gastrointestinal tract symptoms in patients treated with Acarbose Tablets are a manifestation of the mechanism of action of Acarbose Tablets and are related to the presence of undigested carbohydrate in the lower GI tract. If any of these effects persist or worsen, tell your doctor or promptly. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended. Swallow the food or liquid right away, making sure not to chew the medication. Drink a glass of water or juice after swallowing the food to make sure all the medication is swallowed. Do not save the medication mixture for later. purchase generic atenolol mastercard canada
Take this medication by mouth, usually 3 times a day at the start with the first bites of each main meal or as directed by your doctor. PrecoseR acarbose tablets to existing therapies for patients with type II diabetes improves long-term blood glucose control, according to final results of the United Kingdom Prospective Diabetes Study. Remember that your doctor has prescribed this because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication not have serious side effects. Hypoglycemia: Because of their mechanism of action, Acarbose Tablets when administered alone should not cause hypoglycemia in the fasted or postprandial state. Sulfonylurea agents or insulin may cause hypoglycemia. Because Acarbose Tablets given in combination with a sulfonylurea or insulin will cause a further lowering of blood glucose, it may increase the potential for hypoglycemia. Hypoglycemia does not occur in patients receiving metformin alone under usual circumstances of use, and no increased incidence of hypoglycemia was observed in patients when Acarbose Tablets were added to metformin therapy. Oral glucose dextrose whose absorption is not inhibited by Acarbose Tablets, should be used instead of sucrose cane sugar in the treatment of mild to moderate hypoglycemia. Sucrose, whose hydrolysis to glucose and fructose is inhibited by Acarbose Tablets, is unsuitable for the rapid correction of hypoglycemia. During treatment initiation and dose titration see below one-hour postprandial plasma glucose may be used to determine the therapeutic response to Acarbose Tablets and identify the minimum effective dose for the patient. Thereafter, glycosylated hemoglobin should be measured at intervals of approximately three months. The therapeutic goal should be to decrease both postprandial plasma glucose and glycosylated hemoglobin levels to normal or near normal by using the lowest effective dose of Acarbose Tablets, either as monotherapy or in combination with sulfonylureas, insulin or metformin. Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. Acarbose. In rabbits, reduced maternal body weight gain, probably the result of the pharmacodynamic activity of high doses of Acarbose in the intestines, may have been responsible for a slight increase in the number of embryonic losses. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. Lab tests may be performed while you use acarbose. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments. Studies on acarbose have been done only in adult patients, and there is no specific information comparing use of acarbose in children with use in other age groups.
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It is a group of symptoms that may result from having part of your removed or from other surgery involving the stomach. The symptoms range from mild to severe and often subside with time. Although you may find dumping syndrome alarming at first, it is not life threatening. You can control it by making changes in what and how you eat. Acarbose is to be used only by the patient for whom it is prescribed. Do not share it with other people. How should I take acarbose? buy hydrochlorothiazide canada
If you have any questions about acarbose, please talk with your doctor, pharmacist, or other health care provider. Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Carefully follow the regular testing of urine or blood glucose schedules given to you by your health care provider. Unlike sulfonylureas or insulin, an overdose of Acarbose Tablets will not result in hypoglycemia. An overdose may result in transient increases in flatulence, diarrhea, and abdominal discomfort which shortly subside. In cases of overdosage the patient should not be given drinks or meals containing carbohydrates polysaccharides, oligosaccharides and disaccharides for the next 4-6 hours.
It is recommended that serum transaminase levels be checked every 3 months during the first year of treatment with Acarbose Tablets and periodically thereafter. If elevated transaminases are observed, a reduction in dosage or withdrawal of therapy may be indicated, particularly if the elevations persist. This contains to help break down and digest fats, starch, and proteins in food. Go for complex carbohydrates, such as vegetables and whole-wheat bread, instead of simple carbohydrates, such as sweet rolls and ice cream. Acarbose is a complex oligosaccharide that delays the digestion of ingested carbohydrates, thereby resulting in a smaller rise in blood glucose concentration following meals. As a consequence of plasma glucose reduction, Acarbose Tablets reduce levels of glycosylated hemoglobin in patients with type 2 diabetes mellitus. Systemic non-enzymatic protein glycosylation, as reflected by levels of glycosylated hemoglobin, is a function of average blood glucose concentration over time. spirotone
If you miss a dose of Glycomet, take as soon as possible. Do not double doses. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs. The native american diet is largely unchanged, except where Western influence has taken over - hence high rates of obesity, diabetes, and alcoholism - they are all interrelated. Now, understand that I am of Western European descent, so I do NOT consider myself an expert on native american diets.